Grey's Anatomy Season 10 Trailer: Who Dies?

Things aren't looking good at Grey Sloan Memorial Hospital.

The first trailer for Grey's Anatomy Season 10 is riddled with tears, explosions and — for one unlucky person — death.

Can Grey's Anatomy go on past Season 10?

Owen (Kevin McKidd) is seen declaring the time of death for an unseen patient, while Derek (Patrick Desmpey) and Bailey (Chandra Wilson) look on in horror. So who dies? Is it the Chief, who was electrocuted in the Season 9 finale? Heather (Tina Majorino), who's seen hitting her head in the promo (and is leaving the show this season)? Or maybe Lauren (Hilarie Burton), after being murdered by Callie (Sara Ramirez) in a jealous rage? 

OK, probably not the latter, but Calzona fans can dream, right?

Watch the trailer below and share your theories on who doesn't make it through the premiere.

Grey's Anatomy returns Thursday, Sept. 26 at 9/8c on ABC.