Remember that dishy New York magazine cover story on Gossip Girl from a few weeks back that strongly suggested that on-screen frenemies Blake Lively and Leighton Meester can't stand each other in real life? Well, at yesterday's CW upfront, Lively, for the first time, responded to the article, taking specific aim at the allegation that she and Meester "avoid each other like the plague" while on set. The blonde bombshell also discussed this week's pivotal episode, and answered the question on the lips of Gossip Girl fans everywhere: What made Serena think she "killed" that dude?!

My complete interview with Lively is below.

Want more Gossip? My interviews with Penn Badgley and Chace Crawford are now playing on your main video page. And there's much more to come, so keep checking back throughout the day!