Cameron and Cuddy, meet your new competition.

In what I'm pretty sure marks her first dalliance with the small screen, House has cast Piper Perabo ( Coyote Ugly, The Prestige) as a potential love interest for Hugh Laurie's crotchety doc in this season's second-to-last episode. As of now, Perabo's on board for one episode, but a source close to the show says there's "definite recurring potential."

So, what do you think? Cameron, Cuddy or Piper? Or are you still holding out hope for a House/Wilson hookup? Sound off below!