The "At Last" singer, 73, was taken to a Southern California hospital on Wednesday and is now on a breathing apparatus. Lupe de Leon, James' manager for 30 years, reportedly said the singer is "in pretty bad shape."
It is unknown when or if James will be able to be released from the hospital. It was recently revealed that James is suffering from terminal leukemia. She is also suffering from dementia and had been receiving at-home care.
She previously battled sepsis this past May and in January of 2010.