Season 4 of Chicago Med will see plenty of drama: Will (Nick Gehlfuss) and Natalie (Torrey DeVitto) won't see eye-to-eye as they plan their upcoming nuptials, Ava (Norma Kuhling) and Connor (Colin Donnell) will have to overcome several roadblocks as Connor tries to get his expensive but groundbreaking new program off the ground, and Ethan (Brian Tee) and April (Yaya DaCosta) will continue to butt heads over Ethan's troubled sister.

More importantly, the ED will be the battleground for a major conflict between Goodwin (S. Epatha Merkerson) and newly-instated COO Garrett (Heather Headley), who both have different ideas about how to maintain the hospital's budget while providing patients with quality care.

"She is a formidable force. She is the brains of the book and the head of the hospital whereas Sharon Goodwin is more the heart and the soul of the hospital," Heather Headley told TV Guide. "They both want what's best for the hospital but they're coming at it from two different aspects and so it causes a little bit of drama."

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Up until now, Goodwin hasn't faced much opposition but Garrett represents an entirely new beast, one who wields enough power to actually stand up to her, meaning there's trouble ahead.

"Goodwin is all about how to financially run [Chicago Med] as smoothly as she can," added S. Epatha Merkerson. "But most important for her is patient care so that's why she and Garrett are having this issue. She's pretty much had the run of the ED and so now, Garrett is someone she has to deal with on a one-on-one basis who is disagreeing with a lot of the decisions that she's making so that's cause for a lot of fireworks."

Brace yourselves, it looks like things are about to get heated between these two!

Chicago Med airs Wednesdays at 8/7c on NBC.

Epatha Merkerson and Heather Headley, <em>Chicago Med</em>Epatha Merkerson and Heather Headley, Chicago Med