According to the Hollywood Reporter, Lena Headey ( The Brothers Grimm, The Cave) will pick up where Linda Hamilton left off and play the title character in The Sarah Connor Chronicles, a Fox pilot set between the second and third Terminator films, and following 15-year-old John's tough-gal mom.... 8 Simple Rules' Kaley Cuoco, who, when she first auditioned for the role last spring, was deemed too young, fought the good fight and has landed the female lead in The Big Bang Theory, CBS' comedy pilot about genius physicists (Johnny Galecki and Jim Parsons) whose lives are turned upside down by a woman (Cuoco).