Carol Ann Susi Carol Ann Susi

Carol Ann Susi, who voiced the never-seen Mrs. Wolowitz on The Big Bang Theory, died Tuesday after a short battle with an aggressive form of cancer, her agency announced. She was 62.

Born in Brooklyn, Susi studied acting at the HB Studio in New York and moved to Los Angeles in the 1970s to pursue an acting career. She played secretary Monique Marmelstein on ABC's The Night Stalker, and also had guest-starring roles on shows including CheersDoogie Howser, M.D.Mad About YouJust Shoot MeSeinfeld and Six Feet Under.

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On The Big Bang Theory, Susi played the mother of Howard (Simon Helberg), whose booming Brooklyn voice was a fixture on the show.

CBS and the producers of The Big Bang Theory released the following statement Tuesday:

"The Big Bang Theory family has lost a beloved member today with the passing of Carol Ann Susi, who hilariously and memorably voiced the role of Mrs. Wolowitz. Unseen by viewers, the Mrs. Wolowitz character became a bit of a mystery throughout the show's eight seasons. What was not a mystery, however, was Carol Ann's immense talent and comedic timing, which were on display during each unforgettable appearance. In addition to her talent, Carol Ann was a constant source of joy and kindness to all. Our thoughts and deepest condolences are with her family during this time, and we will miss her greatly."

Susi is survived by a brother.