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When Big Bang Theory Nerds Collide

The Big Bang Theory created good chemistry by pairing Sheldon (Jim Parsons) with Amy (real-life brainiac Mayim Bialik). After Blossom, the former teen star earned her doctorate at UCLA, making her Hollywood's most famous actress with a Ph.D. We asked Bialik about her other life and our chances of seeing new couple Sheldon and Amy (aka "Shamie") get physical this season...

Steve Gutierrez

The Big Bang Theorycreated good chemistry by pairing Sheldon (Jim Parsons) with Amy (real-life brainiac Mayim Bialik). After Blossom, the former teen star earned her doctorate at UCLA, making her Hollywood's most famous actress with a Ph.D. We asked Bialik about her other life and our chances of seeing new couple Sheldon and Amy (aka "Shamie") get physical this season.
TV Guide Magazine: Like your character, Amy Farrah Fowler, you're a neurobiologist?
Bialik: A genuine nerd, but I'm a neuroscientist. The difference is not huge, but in the nerd world, there are subtle differences. My field was psychoneuroendocrinology.
TV Guide Magazine: What was the title of your thesis?
Bialik: "Hormone Fluctuations and Obsessive-Compulsive and Affiliated Behavior in Adolescents With Prader-Willi Syndrome."
TV Guide Magazine: In English?
Bialik: I studied adolescents with a genetic syndrome with high rates of OCD.
TV Guide Magazine: OCD? Not unlike Sheldon?
Bialik: Not unlike, but I think with him it's more a spectrum disorder. We were discussing some behavior Sheldon was enacting, and Bill Prady said to [cocreator] Chuck Lorre, "I would ask Mayim. She's the neuroscientist." I get to sort of be, like, actor crew and also nerd crew.
TV Guide Magazine: At first meeting, Amy insisted "coitus" was "off the table." Any possibility now?
Bialik: Not that I know of. I think for Sheldon, some of the resistance to touch has to do with hygiene. I really can't figure a way unless they were both in plastic suits and blindfolded, and I don't mean for that to sound kinky.
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