The brand is on HGH!

Desus & Mero, Showtime's upcoming talk show from Bronx-bred comedians Desus Nice and The Kid Mero, will debut Feb. 21 with another Bronx icon as its first guest: Rep. Alexandria Ocasio-Cortez, the sensational freshman congressperson representing neighborhoods in the Bronx and Queens.

The AOC x Bodega Boys collab was announced in a short video Wednesday, wherein the representative makes the borough's signature sound: "YERRRRR!"

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Desus and Mero are probably gonna try to get her to make Salsa Con Fuego a national historic site, tell Donald Trumpito he can catch these hands and declare that white people are genetically recessive Yakubian creations.

(If none of these references make sense to you, you're gonna have to watch Desus & Mero and get on their level. Your funny bone will thank you.)

Desus & Mero premieres Thursday, Feb. 21 at 11/10c on Showtime.

(Disclosure: TV Guide is owned by CBS Interactive, a division of CBS Corporation, Showtime's parent company.)

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