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24 Episodes 1998 - 1999
Episode 1
Wed, Sep 30, 1998
Dr. Shutt begins to do surgery again although his future in psychiatry is uncertain. A "suicide doctor" tries to get the hospital transplant committee to use organs that were not harvested properly, and promises one to Austin's patient without her consent. Sarin gas is released in a bank threatening many lives including Hancock's, who risks his own to save others. Wilkes loses it after the incident on the heels of the previous shooting at his son's school, leading him to take a drastic step. Diane returns to work after her maternity leave.
Episode 2
Wed, Oct 7, 1998
Austin has to give a physical exam to a former astronaut scheduled to fly the space shuttle. An old friend of McNeil's arrives at Hope dying of pancreatic cancer. Shutt treats a young rabbinical student who attempted suicide.
Episode 3
Wed, Oct 14, 1998
Watters sends an uninsured child to County for risky heart surgery; a national magazine profiles Catera; nobody knows a mysterious observer (Eric Stoltz).
Episode 4
Wed, Oct 21, 1998
Grad suspects parents of starving a baby; Shutt and Catera clash over a diagnosis; Austin announces her NASA plans and is demoted; Dr. Yeats uses intuition.
Episode 5
Wed, Oct 28, 199860 mins
Dr. Waters has a fever and gets a visit from Alan, the Chicago Hope lawyer who was shot and killed. Camille returns and her and Aaron rekindle their romance, Dr. Geiger and Dr. Nyland also pay a visit. A man has multiple surgeries while his disabled wife waits and Dr. McNeil gets an unexpected reward.
Episode 6
Wed, Nov 4, 1998
Austin suspects a patient is misusing Viagra; despite a patient's religious objections, McNeil gives a blood transfusion; a musician fears medication will destroy his creativity.
Episode 7
Wed, Nov 11, 1998
Dr. Hancock gets caught up in a political movement after accusing a white police officer of shooting a homeless African-American; Dr. Austin learns to fly a plane.
Episode 8
Wed, Nov 18, 1998
A TV star is rushed into the emergency room after a fall and dies suddenly, causing a news crew to hound Drs. McNeil and Yeats for the real cause of death.
Episode 9
Wed, Nov 25, 1998
Thanksgiving at Chicago Hope. Billy's mom shows up for Thanksgiving and goes into labour. A 13 year old Buddhist Llama is admitted under Dr. Yates with cardiac concerns and anxiety. Aaron has Thanksgiving with an actor who thinks he is Jesus.
Episode 10
Wed, Dec 9, 199860 mins
Dr. Wilkes faces certain fears when his son shoots a friend while playing with his father's handgun; one of Dr. Shutt's patients is attracted to him.
Episode 11
Wed, Dec 16, 1998
A girl on Dr. McNeil's basketball team almost dies from brain injuries incurred during a game; Dr. Yeats feels his patient should not have heart surgery.
Episode 12
Wed, Jan 13, 1999
Shutt has difficulty coping with a patient's death; Kronk is tempted by the advances of his daughter's baby sitter.
Episode 13
Wed, Jan 20, 1999
Yeats and Austin are snowed in at a remote cabin during a yoga retreat, while Sara becomes dangerously ill.
Episode 14
Wed, Feb 3, 1999
Grad is accidentally exposed when she cuts herself while delivering the baby of an HIV-positive woman.
Episode 15
Wed, Feb 10, 199960 mins
McNeil performs a hand transplant; Austin becomes a crewmember on the space shuttle; Watters' ailing childhood friend asks him to donate a kidney.

Episode 16
Wed, Feb 17, 1999
Jack gets bad news and has to return home. Billy's friend needs a new heart. Dr. Cacaci is peddling a line of home and beauty products. Jack and Lisa's relationship hits a crossroad.
Episode 17
Wed, Mar 10, 1999
Catera tries to get a terminally ill patient into a cancer test study. One of Shutt's patients confesses to murder. Cronk struggles with the decision to put his seriously ill dog to sleep.
Episode 18
Wed, Mar 24, 199960 mins
An overweight patient makes Keith re-evaluate his own life choices. A visit from a former supervisor has Kate reliving their past relationship and re-evaluating her own relationships with others. Diane gets test results.
Episode 19
Wed, Mar 31, 1999
Parents facing a horrible situation want to gamble on future technology. Aaron's psych experiment goes horribly wrong. An Alzheimer's patient confuses Jack with someone from her past.
Episode 20
Wed, Apr 14, 1999
A new mother is shocked when she gives birth to white and black babies; Dr. Austin makes a rude remark and is threatened with a lawsuit.
Episode 21
Wed, Apr 21, 1999
A multiple birth has Chicago Hope hopping. Bobby and Diane help a very unusual patient. Aaron's dog needs therapy.
Episode 22
Wed, Apr 28, 1999
A man from Kate's past makes a brief but dramatic reappearance. A pregnant cancer patient faces an impossible choice. Dr. Cacaci makes a retaliatory allegation against Philip.
Episode 23
Mon, May 17, 1999
Mass casualties arrive from a rave. Among them are drug overdoses, a young woman who was raped, and a young man who changes the course of Kate's life. Philip continues to refuse to participate in his own defense.
Episode 24
Wed, May 19, 1999
Jeffrey Geiger returns having bought controlling interest in the hospital and he fires Austin, Kronk, Yeats, Catera, and Hancock. They decide to pursue their options. Aaron consults with the new pediatric surgeon, Gina Simon about a new born baby. And a young surgeon who was hired by Austin before her dismissal arrives and Geiger puts her to work.