Sherry Stringfield courtesy United Talent Agency Sherry Stringfield courtesy United Talent Agency

She isn't doling out tough love as ER's Dr. Susan Lewis anymore. On In Plain Sight (Sundays at 10 pm/ET, USA), Sherry Stringfield plays against type as a wife in denial about her shifty art-dealer spouse. Our prescription: You've gotta watch. - G.J. Donnelly

TV Guide: How does your character land in Witness Protection?
Sherry Stringfield:
There are these cool art people in New York, and she discovers this big scam that's going on and a murder happens. She has to go into witness protection because people are making millions off of this. She's very devoted to her husband, and it's different from what I normally play. She's very naïve about his behavior and keeps thinking this a great guy and nothing's going on in the face of him being basically arrested.

TV Guide: What attracted you to the show?
I think it's a cool idea. I'm surprised no one had done it. What does happen to people in the witness protection program? I like the style of it. I love New Mexico. I think Mary McCormack is a great actress.

TV Guide: You've been very busy since ER with stints on Shark and Tell Me You Love Me. What roles excite you?
It's not necessarily the role, but it's more the project. I just did the remake of [the 1987 horror film] The Stepfather. I play a lesbian, and my girlfriend is murdered. I like difference. Something new, a different perspective. ER was a different perspective on the medical perspective. NYPD Blue was a different perspective on cops.

TV Guide: Would you join another series?
If it was the right series, yeah. If was something innovative, I think I could.

TV Guide: You're not a doctor but you played one on ER for 11 seasons. Do you get requests for medical advice?
[ Laughs] Thank God, no! 'Cause they would be in some big trouble.

TV Guide: Which of the ER doctors would you want treating you?
Dr. Lewis! Rock and roll!

TV Guide: Reflections on ER?
It's a chief part of my life. I guess how hard it is for a series to keep fresh and good and stay true to character. That becomes harder and harder. You have to stay on it even more. You have to fight.... [ ER] isn't a soap opera. This isn't about my hair. It's a successful machine and it requires a lot of work. You have to stand your ground. A great lesson for me.