Grey's "Home-wrecker" Lauren Stamile on Rose and Derek's Future

In tonight's Grey's Anatomy (9 pm/ET, ABC) — the last original episode filmedbefore the writers' strike — Derek dealswith the repercussions of kissing nurseRose after they bonded during a particularlyhairy brain surgery a few weeks ago. Played by Oklahoma native Lauren Stamile,Rose is scheduled to appear in at least seven episodes. And with tonight onlymarking Stamile's fourth appearance, we can expect to see Rosecomplicating the Derek-Meredith romance a bit more. As Stamile sayswith a laugh, "Something else has to happen!"

TV Guide: Tonight, Derek deals with the aftermath of kissing Rose. What more can you tell us?
Lauren Stamile: All I can really say is that things go a little bit differentlythan people would expect. [Derek and Rose] are not going offinto the sunset.

TV Guide: How does it feel to be McDreamy's latest paramour?
Stamile: [Laughs] Great!Every once in a while it'll hit me and I'll think, "That's me? Just a girlfrom Oklahoma!" But those are wonderful shoes to try to fill.

TV Guide: Do you fear that you'll be labeled a home-wrecker for keeping Derek and Meredith apart?
Stamile: Absolutely. As a fan of the show and as a romantic,I'm always rooting for Derek and Meredith. So I think that ifI am, then other people have to be! But I try to stay off the blogs....If I start to read [fan comments], it's going to inform my work.

TV Guide: You did a spot-on job of playing Kate Jackson in the 2004 TV-movie Behind the Camera: The Unauthorized Story of Charlie's Angels.
Stamile: I worked hard on that! I had about a month to prepare and I rentedeverything that Kate Jackson was in. I'd sit there and start and stopand say words and try to get the movements. As a young actor, youdon't really get the opportunity to play someone far from yourself.

TV Guide: You've also guest-starred on some big shows, including Heroes, CSI: Miami and Without a Trace. How do those experiences compare to Grey's?
Stamile: The biggest difference is that in most of those jobs, I was justthere for a week, a quick arc and then gone. This is more challengingbecause I have to try to learn about who this person is. And as a fanof [Grey's], that makes it even more exciting. I still can't quite believeit. I'm doing exactly what I want to do.