Five years after the death of his scientist father in The Fly (1986), whiz kid Martin Brundle is kept under lock and key in the labs of Bartok Industries. With the teleportation device now in the hands of the duplicitous CEO, Anton Bartok, Martin is eager to perfect the ambitious matter transfer project and vindicate its inventor. However, he is running out of time. And as the dormant alien chromosomes inside him spread like wildfire, it is only a question of when the insect within will take over. But the disease has a purpose. Who can prevent it from turning Martin into something else?