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In 1909 Xochimilco, María Candelaria and Lorenzo Rafael long to marry, but the odds are against them. María Candelaria is ostracized for being a prostitute's child, and the couple faces the greed of Mr. Damian, the town's shop owner, who secretly desires María. When María falls sick with malaria, Lorenzo Rafael steals a quinine bottle from Damian's shop, unleashing tragedy for the lovers.
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