Dr. John Worthing sacrifices his personal life when he leaves his fiancée, Claire Eaton, to test his serum in a plague-ridden country far to the north. Claire, believing that her sweetheart has died in this faraway land, accepts the attentions of the unscrupulous Hugh Conway who is simultaneously courting Eva Cartier, a young nurse, who leaves him after discovering his true nature. Meanwhile, Worthing returns and, disillusioned by Claire's disloyalty, degenerates into an opium addict. Hospitalized after a brawl, Worthing is recognized by his old friend Elliot, who entrusts him to Eva, in whose care he is rehabilitated and with whom he falls in love. Discovering Eva's newfound happiness, Conway enlists Claire's aid in breaking up the happy couple, but his plans are thwarted when he drowns while carrying out his scheme.
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