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Iris Atwood hosts "Dear Iris," a live podcast from her home where she offers listeners advice on their relationship problems, despite not having a counseling degree. She's buoyed by support from best buddy/co-host Zach Morales, and producer/fiancé Henry Quinn. But Iris' younger sister Kylie, a psychology major, isn't convinced that Iris' "from the heart" advice is of any value, which creates ongoing tension between them. One night Iris offers advice to a troubled, unstable single mom, Vanessa. Vanessa is deeply concerned that she's losing control of her disrespectful, ornery teen son Dylan. Iris tells Vanessa to stand firm and practice "tough love," and wishes her well. When Vanessa takes her advice, a struggle ensues, and Dylan dies. Vanessa secretly holds Iris responsible. Six months later, Vanessa enters Iris' life, bent on revenge.
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