Buffington-Quaid previously filed for divorce in March, but later withdrew the petition. In the latest filing, she's asking for full custody of the couple's 4-year-old twins, though Quaid, who is currently starring on Vegas, would get visitation rights, according to TMZ.
The couple were married in 2004 and made headlines in 2007, when their newborn twins nearly died after being given an overdose of heparin at a California hospital. It's the third marriage for Quaid, who was previously married to Meg Ryan and P.J. Soles.