Jonas will play a computer hacker involved in a case that the 5-0 team is investigating whose motives might be even more complicated than they suspect.
"Nothing makes this show more fun than incorporating well-known, talented actors as guest stars on our show," executive producer Peter Lenkov said in a statement. "We're all thrilled to have Nick Jonas join our Ohana."
Jonas, whose previous TV credits include Smash, Mr. Sunshine and Last Man Standing, joins an impressive list of guest stars in Season 4, including Chi McBride, Carol Burnett, Tim Daly, Henry Ian Cusick, Jorge Garcia, Terry O'Quinn, Rebecca De Mornay, Taryn Manning and Rumer Willis.
Hawaii Five-0 moves to Fridays this fall beginning Sept. 27 at 9/8c on CBS.
(Full disclosure: TVGuide.com is owned by CBS.)