Loosely based on the 1987 CBS series about an ADA and a noble man-beast who make a connection, the updated love story stars Smallville's Kristin Kreuk as Catherine Chandler, a cop who intersects with Vincent Keller (Jay Ryan), who was turned into a beast after a faulty military experiment.
MacFarlane, who will appear in the second episode of the freshman series, will play Philippe Bertrand, the exacting yet talented artistic director the of the Bertrand Ballet Company who's intrinsically involved in his dancers' lives. Catherine will investigate the company after their prima-ballerina is murdered.
The 32-year-old actor is well-known for playing Scotty Wandell, the husband of Matthew Rhys' Kevin Walker, on Brothers & Sisters.
Beauty and the Beast premieres Thursday, Oct. 11 at 9/8c on The CW. Will you be watching?