- Began acting as a child, appearing on such shows as Highway to Heaven, My Two Dads and The Wonder Years.
- Studied acting for several years at the Beverly Hills Playhouse, founded by famed teacher and director Milton Katselas.
- Is a member of the Church of Scientology.
- Was nominated for Best Supporting Male Actor at the 2001 Independent Spirit Awards for his role in Sam Raimi's stylish 2000 thriller The Gift.
- Learned to speak Italian for the 2002 film Heaven.
- Has a strong interest in computer graphics and is a partner in the company Stereo D, which converts 2D images into 3D.
- 2007, Emmy — Outstanding Guest Actor in a Comedy Series: Nominee
- 1998, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Nominee
- 2001, Independent Spirit Awards — Best Supporting Male: Nominee
- Lucia Ribisi — Daughter
- Marissa Ribisi — Sister
- Al Ribisi — Father
- Carla Azar — Ex-significant Other
- Gay Ribisi — Mother
- Gina Ribisi — Sister
- Agyness Deyn — Ex-wife
- Mariah O'Brien — Ex-wife
- Cat Power — Ex-significant Other
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- Birth Name: Antonio Giovanni Ribisi
- Birth Place: Los Angeles, California, United States
- Profession: Actor
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Slaying the enemies of Jesus with the angel Castiel