Premise

The story revolves around five surgical interns and their supervisors, showing their personal and professional lives.

Active Cast

Ellen Pompeo Meredith Grey
Justin Chambers Alex Karev
Chandra Wilson Miranda Bailey
James Pickens Jr. Richard Webber
Sara Ramirez Callie Torres
Kevin McKidd Owen Hunt
Jessica Capshaw Arizona Robbins
Jesse Williams Jackson Avery
Sarah Drew April Kepner
Jerrika Hinton Stephanie Edwards
Catarina Scorsone Amelia Shepherd
Kelly McCreary Margaret "Maggie" Pierce

Former Cast

Patrick Dempsey Derek Shepherd
Sandra Oh Cristina Yang
Katherine Heigl Izzie Stevens
Isaiah Washington Preston Burke
T.R. Knight George O'Malley
Eric Dane Mark Sloan
Kate Walsh Addison Shepherd
Chyler Leigh Lexie Grey
Loretta Devine Adele Webber
Kate Burton Ellis Grey
Sarah Utterback Nurse Olivia
Chris O'Donnell Finn Dandridge
Jeff Perry Thatcher Grey
Jeffrey Dean Morgan Denny Duquette
Kali Rocha Sydney Heron
George Dzundza Harold O'Malley
Debra Monk Louise O'Malley
Mare Winningham Susan Grey
Kyle Chandler Dylan Young
Diahann Carroll Jane Burke
Brooke Smith Erica Hahn
Edward Herrmann Norman Shales
Mary McDonnell Virginia Dixon
Amy Madigan Dr. Wyatt
Melissa George Sadie Harris
Robert Baker Charles Percy
Nora Zehetner Reed Adamson
Kim Raver Teddy Altman
James Tupper Andrew Perkins
Gaius Charles Shane Ross
Tessa Ferrer Leah Murphy