The Big Bang Theory (CBS)
Premieres: Thursday, Sept. 27 at 8/7c

Where We Left Off: Howard and Bernadette had a rooftop wedding just days before he blasted off into space, which the whole gang watched wistfully on TV. Leonard also awkwardly proposed to Penny in bed.

What's Next: Howard will still be in space for a few episodes when Season 6 returns, but when he does land back on Earth, he will be emboldened by his other-worldly adventure. Howard and Bernadette's living situation will also be resolved (to live with Mrs. Wolowitz or to not?), while Leonard and Penny will try to get on the same page about marriage. Sheldon and Amy's baffling relationship will progress, and Raj will finally get a girlfriend! Hopefully it's not Siri again.