Wendie Jo Sperber with Tom Hanks Wendie Jo Sperber with Tom Hanks
Wendie Jo Sperber, best known for playing cross-dressing Tom Hanks' confidante on the early-'80s sitcom Bosom Buddies, lost an eight-year battle with breast cancer on Tuesday. "The memory of Wendie Jo is that of a walking inspiration," says Hanks in a statement. "She met the challenges of her illness with love, cheer, joy and altruism. We are going to miss her as surely as we are all better for knowing her." Sperber's credits also included Michael J. Fox's big sister in all three Back to the Future movies.