Potential Grey's Anatomy spoilers follow! Read at your own risk...

Grey's Anatomy may have just given away one of the season's biggest events in an episode trailer.

In the preview for next Thursday's (May 10) episode, Grey's Anatomy fans were told that April (Sarah Drew) will be involved in a serious accident. While Meredith (Ellen Pompeo) swears they aren't going to lose her, the final moments of the trailer show Jackson (Jesse Williams) rushing into the emergency room and throwing himself over a comatose — or potentially DEAD — April.

She's laying perfectly still with tubes coming out of her mouth, and there's no way they'd let him on top of her if they were still working on bringing her back to life. Combine that with Meredith bursting into tears and it seems pretty obvious that April will be losing her life in the penultimate episode of the season.

Grey's Anatomy: April and Arizona's Departures Are Beginning to Take Shape

It was announced in March that series regulars Sarah Drew and Jessica Capshaw, who plays Arizona Robins, would be leaving the show at the end of the season. While Arizona all but confirmed that she'll be taking her daughter back to New York as her exit plan, many — including TV Guide — have theorized that April's departure will be much more tragic. She has a baby on the show with Jackson, who is remaining on the show. There's very little that would take her away from baby Harriet other than a death.

To make matters worse, Thursday's episode included a scene where Jackson put aside money for Harriet's future so she wouldn't be affected by the Harper Avery lawsuits. April sincerely thanked him and compared the gesture to a fable from the Bible. Jackson didn't resent the comparison, which shows the two have really come to a peaceful place in their coparenting relationship. With Harriet's financial future secure, the show was signaling loose ends being tied up before tragedy strikes for April.

Even if you saw it coming, the trailer proves that you definitely need tissues ready for next week's episode. This is going to be rough.

Grey's Anatomy airs Thursdays at 8/7c on ABC.

Sarah Drew, <em>Station 19</em>Sarah Drew, Station 19