Little Grey's death was by far the most shocking and emotional of the season — especially since the ABC medical drama killed her off only 20 minutes into the finale. We were a blubbering mess when Mark held Lexie's hand and told her how they would someday be married with kids. But we really lost it when Meredith realized she'd never get to say goodbye to the sister she almost never knew. Even though Lexie's time was brief, we're glad we got to know her.

Everyone knew Charlie Harper would be gone this season, but how would Chuck Lorre & Co. write out the hedonistic playboy? In the grossest way possible. Charlie was hit by a Parisian train and exploded "like a balloon full of meat," but that's not even the gross part. At his memorial service, his former conquests put the "fun" in funeral, listing all the STDs he's given them. While Ashton Kutcher's Walden Schmidt has been a competent replacement, he's still no Charlie. And know Lorre knows that too: He brought Charlie's spirit back not once but twice in five months.

They were doomed from the start. Almost immediately after they moved into the infamous "Murder House," things got weird when Vivien had sex with a man in a rubber suit who she believed to be her husband Ben. (It turned out to be Tate, the boyfriend of Vivien's daughter Violet. Oh, and Vivien got pregnant — by both Ben and Tate.) Realizing Tate's betrayal, Violet commits suicide. Vivien ultimately dies in childbirth and Ben is hanged by the ghost of his dead ex-mistress. But hey, the Harmons were reunited as a ghost family! Happy ending?

Was it a complete surprise that Wisteria Lane's sexiest plumber would bite the bullet? Sadly, no. But Mike's murder at the hand of a wise guy loan shark was still heartbreaking for fans who spent years hoping for a happy ending for Mike and Susan. But it wasn't all tears: Mike's death inspired Julie to keep her baby, giving Susan new purpose as a grandmother.

Mike's death was a gut-punch, but Mrs. McCluskey's send-off felt like a final hug from an old friend. After testifying that she committed Alejandro's murder in order to free Bree, Karen went home, listened to Johnny Mathis' "Wonderful! Wonderful!" and drifted away before eventually being reunited with the other ghosts of Wisteria Lane. Marc Cherry promised to never kill Mrs. McCluskey before the end, and when he did, he did it with style.

Besides being a terribly kept secret, Shane's death also had the misfortune of coming one week after Dale met his demise. (R.I.P. to you too, old friend!) But Shane's final moments didn't lose any of their power, thanks mostly to the season's worth of tension between Shane and his best friend Rick that preceded them. Did Rick kill Shane just to rid himself of the man who stole his wife and questioned his every move, or was it pure self-defense? We may never know, and in that way, Shane's morally gray spirit continues to live on.

Uncle Bobby died twice. He first bought the farm after Dick Roman shot him in the head, but he stuck around, as a ghost tied to the flask that Dean carried. After becoming too vengeful while helping the Winchester boys with their monster-hunting activities, Bobby decided to die for good by having them burn the flask. His presence will be sorely missed, not only for his curmudgeonly dose of common sense, but also because he handled the bulk of the supernatural research and represented a tie to Winchesters' late father.

The former head of Division fell to his death — landing on the glass ceiling of the prison he escaped from earlier in the season — after Nikita willingly let go of his hand as he was dangling over the edge of a chasm. It's the end of an era for the series: In addition to being a sick father figure of sorts to Nikita when she first entered the underground operations, the diabolical mastermind was also the source of many double-crosses and plot twists. That, we will miss.

The dissolute Roman was last seen willingly falling over a cliff while clutching the baby she had just cut out of her friend's womb. You see, Lucretia's mind was a little muddled after her near-death experience last season, and she believed that dying with this baby would create a mini-family with her late husband Batiatus in the afterlife. The world of Spartacus won't be the same without her looney, cutthroat ways and colorful wigs.

The young, brash claimant to the Iron Throne was just prepping for the next day's battle, minding his own business, when a magical shadow creature in the shape of his brother stabbed him. How rude! His death had widespread implications: Not only was the War of Five Kings diminished by one, but his followers also split into factions to support the other claimants, thus shifting the balance of power. Renly brought a positive, humorous and personable approach to ruling, something that will be sorely missed in the grim world of Westeros.

It's one thing to be injured in the line of duty, but it's another to be stabbed in the gut by your ageless grandfather who had seemingly time-traveled to the future. Sure, we're guessing Rebecca would have been revived by the colloidal silver in the Season 2 premiere, but we'll never know since Fox axed the series.

No TV death was more memorable or shocking this season — hell, in any season — than Gus' two-faced demise. After emerging ostensibly unscathed from a bomb blast, it seemed like the cold-blooded meth kingpin was immortal. But an artful camera pan revealed Gus' gruesome but awesome half-disfigured face before he dropped dead. We would have loved to see more Gus in the final season, but if he had to go, this is the way to do it. And can anyone look at a brass service bell the same way again?

Alaric went from being a teacher who drinks too much and sleeps on his student's couch to being an evil wannabe vampire slayer. After Original Witch Esther put a spell on Alaric which bound him to Elena, his death ultimately came when Elena drowned in the season finale. While we're glad the Mystic Falls gang has one less enemy, we'll miss the old Alaric who had a genuine fatherly love for Elena and Jeremy.

Graham was Once's first true casualty, which served as proof that it's not necessarily a good thing for a character to remember his or her past in fairy tale land. Still, Graham's death was the catalyst for Emma to become the Sheriff of Storybrooke and take Regina down from the inside. And as we saw in the finale, the Huntsman can still return in flashback. Please sirs, can we have some more?

Yes, Tyler was a manipulative, insane, pathological liar. But despite (because of?) those qualities, Revenge fans are still mourning his murder on the beach. He had to die so that Daniel could live, but Tyler's unpredictable moves — like when he held a gun to Emily's head at Daniel's birthday party — made this maniac both a great opponent for Emily and a hard character to replace.

After first popping up as a charming-but-cocky pro golfer in Season 2, Jack came back for another round, — this time with a medical problem! Unfortunately, Jack's advanced lupus was far from Hank's normal one-and-done medical cases and the disease eventually took Jack's life after he skipped out on his dialysis treatment. The death of a patient, as well as a friend, hit Hank especially hard and caused him to leave HankMed at the end of Season 3 — a move sure to be felt when the show returns this summer.

Gemma learned the hard way one of the truths of this short-lived CW series: If you threaten to reveal the show's big secret — that one twin sister is living as the other — you're going to get killed. Her death, however, did show a softer side of Siobhan. Or at least the side of her that shot Gemma's killer in the head after she arrived too late to save her ex-best friend whose husband she was sleeping with. Vengeance isn't pretty, folks.

It may seem a little silly to get attached to a wine glass, but the murder of Jules' beloved stemware was a tough loss for the cul-de-sac crew. Ellie and Andy's son Stan solidified his "devil child" status when he inexplicably broke Big Carl right in front of Jules. Luckily, she had a wedding to plan and was able to move on to Big Lou shortly after the funeral. Here's hoping Carl is in the big cabinet in the sky clinking rims with Big Joe and serving copious amounts of wine to the masses. Cheers!

Although neither of these women died, they deserve special mentions. After years of serving their respective crime-fighting teams, both women made graceful exits with bigger, better jobs on the horizon. (Catherine is heading to the FBI while Prentiss was being courted by Interpol in London.) That, of course, leaves the door open for return visits, for which we will remain hopeful. So long as the shows don't bring them back just to kill them off.