- Born in Macau but grew up in New York City and Pittsburgh.
- Fell in love with acting after performing on stage in the third grade.
- Pursued acting in college before returning to New York to appear in plays, such as Redwood Curtain and Speed-the-Plow.
- Became the first Asian actor to appear as a regular on a soap when she took the role of Lien Hughes on As the World Turns.
- Broke into movies with a starring role in The Joy Luck Club in 1993.
- In 1995, was cast in the recurring role of medical student Deb Chen on the first season of ER; later became a series regular.
- Was the title voice of the 1998 animated Disney film Mulan.
- Made her Broadway debut in 1998 appearing in David Henry Hwang's Golden Child.
- As an accomplished voice-over artist has provided voices for numerous films and TV shows, including Final Fantasy: The Spirits Within; Jimmy Neutron; The Batman; and Phineas and Ferb.
- Played Judge Linda Harris on Two and a Half Men and Camille Wray on SGU Stargate Universe.
- Formed Innovazian Records with her husband to promote Asian-American artists.
- Her name means "enlightenment."
- 2000, Screen Actors Guild Awards — Outstanding Performance by an Ensemble in a Drama Series: Nominee
- Cooper Dominic Zee — Son
- Soo Lim Yee — Stepfather
- Eric Michael Zee — Husband
- Jonathan Wen — Brother
- Leong Yee — Half Brother
- Michaela Zee — Daughter
- Lin Chan Yee — Mother
- Carnegie Mellon University, Pittsburgh, PA (BFA in Drama, 1986)
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- Birth Name: Ming-Na Wen
- Birth Place: Coloane Island, Macau
- Birthday: November 20, 1963, Scorpio
- Profession: Actor
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