- Danced with the Pennsylvania Ballet Company, the American Ballet Theatre and the San Francisco Ballet.
- Made a series of commercials for Burger King before her film debut in Jaws 3-D (1983).
- Turned down the role of Amanda in Some Kind of Wonderful (1987), but reconsidered after urging from the director, who became her husband.
- Won a 1999 TV GUIDE Award for her work in Caroline in the City.
- Appeared on the 2006 Fox reality series Celebrity Duets, and performed two duets with Belinda Carlisle.
- Also in 2006, directed the cable film Jane Doe: The Harder They Fall and also directed a 2008 cable film, Jane Doe: Eye of the Beholder. (She starred in both films.)
- Appears in the 2011 Clint Eastwood-directed drama, J. Edgar, starring Leonardo DiCaprio. She called working with DiCaprio "one of the most amazing days of my life" and joked that the star may have been annoyed that day when she mentioned her husband had once made a macaroni-and-cheese ad with him.
- 1996, People's Choice Awards — Favorite Female Performer in a New TV Series: Winner
- Zoey Deutch — Daughter
- Andrew Thompson — Brother
- Cliff Thompson — Father
- Howard Deutch — Husband
- Barbara Thompson — Mother
- Madelyn Deutch — Daughter
- Dennis Quaid — Ex-fiancé
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- Birth Name: Lea Katherine Thompson
- Birth Place: Rochester, MN
- Profession: Actor, Ballet dancer
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