- Worked as a waitress and as an exercise instructor while pursuing an acting career.
- Studied at the Actors Studio in New York.
- Appeared as a dancer on Club MTV.
- Says she turned down a recurring role on The Sopranos because it would have required her to appear in sex scenes.
- Was originally cast as the second-oldest sister in Related. After shooting the pilot, however, the show was reworked to make her character the oldest sibling.
- Revealed in 2011 that she had been diagnosed with celiac disease; she subsequently opened a gluten-free bakery in New York and released a book, Jennifer's Way, in 2014 about her struggles with the disease.
- 2005, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Winner
- 2006, Critics' Choice Awards — Best Acting Ensemble: Winner
- Louis Dowler — Fiancé
- Cameron Mathison — Ex-significant Other
- Benjamin Bratt — Ex-significant Other
- Bradley Cooper — Ex-husband
- Phyllis Esposito — Mother
- Chris Schupp — Ex-significant Other
- Robert Esposito — Father
- Mark Philippoussis — Ex-fiancé
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- Birth Place: Brooklyn, New York, Untied States
- Profession: Actor
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