- Best known for playing "Shoeless" Joe Jackson in Eight Men Out and Dish Boggett in the miniseries Lonesome Dove.
- Briefly played minor-league baseball for the Kenosha Twins.
- Is close friends with NHL defenseman Chris Chelios, who is godfather to Sweeney's son, Cade.
- In 2008, flew a CH-46E helicopter in squadron HMM-364, "The World Famous Purple Foxes," in Iraq while visiting troops to promote his movie Two Tickets to Paradise.
- Cade Sweeney — Son
- Ashley Vachon Sweeney — Wife
- Kathleen — Sister
- Barbara — Sister
- Tommy — Brother
- Attended Tulane University, New Orleans, LA; New York University, Tisch School of the Arts, New York, New York (BFA in Drama, 1984)
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- Birth Name: Daniel Bernard Sweeney
- Birth Place: Shoreham, NY
- Birthday: November 14, 1961, Scorpio
- Profession: Actor, Writer, Director
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Grey's Anatomy is obviously a big influence on Tay Tay