- Formed a comedy filmmaking group called The Lonely Island with longtime friends Jorma Taccone and Akiva Schaffer; produced a series of popular online shorts, including The O.C. parody "The 'Bu."
- Worked as an assistant on the ABC sitcom Spin City.
- Joined Saturday Night Live in 2005 as a featured player and was promoted to full cast member in 2006.
- Made his big-screen debut playing stuntman Rod Kimble in the 2007 comedy Hot Rod.
- Hosted the 2009 MTV Movie Awards.
- Best known on SNL for his Digital Shorts, including "Lazy Sunday," "Dick in a Box," "Motherlover" and "Jack Sparrow."
- 2010, Emmy — Outstanding Original Music and Lyrics: Nominee
- 2007, Emmy — Outstanding Original Music and Lyrics: Winner
- 2014, Screen Actors Guild Awards — Outstanding Performance by an Ensemble in a Comedy Series: Nominee
- 2009, Emmy — Outstanding Original Music and Lyrics: Nominee
- 2011, Emmy — Outstanding Original Music and Lyrics: Nominee
- 2014, Golden Globe — Best Performance by an Actor in a Television Series - Comedy or Musical: Winner
- 2015, Emmy — Outstanding Writing for a Variety Special: Nominee
- Margie Samberg — Mother
- Darrow — Sister
- Johanna — Sister
- Joanna Newsom — Wife
- Joe Samberg — Father
- Attended University of California, Santa Cruz, Santa Cruz, California, United States; New York University, Tisch School of the Arts, New York, New York, United States
- Birth Place: Berkeley, California, United States
- Profession: Actor, Comedian, Screenwriter
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