Began modeling after being approached by a modeling scout in Paris; appeared in campaigns for Calvin Klein and Armani
Studied acting at New York's famed HB Studio
Made his film debut in the 1999 Barry Levinson drama Liberty Heights
Both he and former Grey's Anatomy costar Chris O'Donnell played D'Artagnan in different incarnations of Alexandre Dumas' classic tale: O'Donnell in 1993's The Three Musketeers and Chambers in 2001's The Musketeer
In 2005, he played a cop in the film Southern Belles and a detective in The Zodiac
Awards
2017People's Choice Awards-Favorite Dramatic TV Actor:winner
2007Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Drama Series:nominated
2006Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Drama Series:winner
2005Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Drama Series:nominated