Tota and Kuromaru kick of their first mission as members of UQ Holder by accompanying Karin. Their duty is to provide security to the citizens from the slums close by. Tota inadvertently ends up befriending an individual from the enemy side.
Eighty years after all the happenings of Negima!, Tota Konoe fantasizes about leaving his town in quest on new adventures but his caretaker Yukihime prevents him from going. Later, he comes to know about his origins and realizes that he has to become an immortal to save Yukihime.