Czar Zoster attempts to invated tromaville by hot air balloon filled with toxic fumes. In order to distract the Toxic Avengers Doctor Killemoff organizes a convention of hideously deformed creatures of superhuman size and strength.
The Toxic Avengers prepare for Yvonne's concert while Czar Zoster and Doctor Killemoff prepare pollute Tromaville. A new superhero Snail Man aids the Toxic Avengers in thwarting Doctor Killemoff's plan.
Doctor Killemoff is replaced by GarBage as the ruthless planetary invador of Tromaville. GarBage's master plan to replace Troma's elderly with evil clones almost succeeds, until the Toxic Avengers recieve help from an unlikely source.
Grody and Doctor Killemoff team up to get rid of the Toxic Avenger once and for all by purchasing a monster truck. The Toxic Avengers start a free cab company. Yvonne becomes jealous of Toxie's relationship with his taxi cab and dumps him.
Doctor Killemoff atempts to destroy the shopping mall in order to sell remote activated smog inducers to the people of Tromaville. A new superhero named Mr. Earth seems to be hurting tromaville more than helping it.
The ruler of smogula discovers a surplus of smog over the toxic waste dump in Tromaville. Mayor Grody Moves the Toxic Avengers into his penthouse when Doctor Killemoff's attemt to forcefully remove them fails.
Dr. Killemoff awaits the arrival of fellow aliens from the planet Smogula to take over Tromaville. He sends his Radiation Rangers to evacuate the elderly citizens of Tromaville from their retirement homes to make room for the landing.