A formerly obese woman hopes to have the excess skin left by her 200 pound weight loss removed; a blind woman seeking to get and train her very first guide dog; a set of Texan twins hoping to lose weight together; a young woman who suffered an accident and needs extensive plastic surgery to repair her face and her confidence; and a man who needs to lose weight to become the super hero he has always wanted to be.
A young woman recovering from a tragic car accident who hopes to become a professional contortionist; a woman struggling to lose 100 pounds; a motocross bike rider who wants to trade her helmet for a beauty queen crown; a man with a lifelong dream of becoming a professional wrestler; and a teacher who has suffered through life with a terrible stutter and hopes to finally make a change, are featured.
A mother and daughter who want to hike the Appalachian trail after the daughter hopefully gets a successful kidney transplant; an obese young woman who hopes to lose 100 pounds; a woman who wants to write a book to tell her father's life story as a tribute to him before he passes; a man searching for his doppelgänger; and a former football hero who hopes to regain the ability to walk.
A woman with an amputated foot pledges to complete a triathlon; a young woman struggling with obesity who wants to lose 100 pounds and wear a bikini for the first time; a blind girl yearning for a seeing eye dog to help her navigate the world; a nurse who wants her own plastic surgery to make her feel more confident; and a couple who has suffered a painful history and want to rebuild their family.
A former police cadet hopes to regain his ability to walk; a woman strives to lose over 50 pounds; a man's protruding ears impact his life; a mother with six daughters puts their life savings into opening a cupcake company; and a woman eager to honor her father's memory participates in a body building competition.
An adopted man searches for his biological family; a woman yearns to lose 60 pounds; a couple with fertility issues hope to have a baby; and a formerly obese young woman wants to have the excess skin from her weight loss removed.
An overweight family pledging to lose over 400 pounds together; a single mom yearning to become a firefighter; a deaf veteran hoping to regain her hearing; a young woman who has been suffering from a tremendous facial deformity her entire life; and a self-proclaimed unicorn looking for love, are featured.
In the series premiere, host Cat Deeley welcomes people who make a commitment to life-changing, year-long goals. A young man pledges to walk again after a car accident left him in a wheelchair; a couple have suffered through 15 years of infertility; a woman struggles to lose 100 pounds; a middle-aged housewife aspires to be a bodybuilder; and a man plans to give his fiancée his own kidney for her life-saving transplant.