When Samar lands in the crosshairs of an unconventional Blacklister, Aram and the Task Force spring into action to find her before it's too late. Meanwhile, Red journeys to Costa Rica to prevent the duffel bag of bones from being sold to the highest bidder at an underground auction.
As Liz works a new angle in tracking Tom's killers, Red looks to find a creative solution to a tax issue in his money-laundering operation. Meanwhile, Aram ventures into the field as the Task Force investigates a mysterious woman behind a deadly viral outbreak.
Red assists the Task Force in tracking a mysterious Blacklister who carefully develops airtight alibis for murderous clients. Meanwhile, Liz's reinstatement at the FBI hinges on an evaluation with a psychotherapist.
When bodies are discovered in abandoned woods, Red points the Task Force toward the Invisible Hand, a group that targets those whose actions are morally reprehensible yet fully legal. Meanwhile, Red steps in to assist one of his employees, and Liz discovers a major clue about Tom's investigation.
When Red goes on the hunt for a legendary treasure, he draws the attention of Abraham Stern, a cunning manipulator who has devoted his life and the lives of many innocents to recovering the fortune that is his birthright. Meanwhile, Liz's quest sends her down a dark path, leading her to study the methods of one of the Blacklist's most dangerous criminals.
In the winter premiere, Liz abandons her old life and seeks out a fresh start in a place where no one knows her history, her name, or the depths of her grief. When an unexpected threat finds her, she is forced to draw on her emotional and physical strength in a brutal fight for survival.
In the fall finale, Tom goes missing; and Liz desperately retraces his steps in order to find him. Meanwhile Red's hunt for the suitcase of bones puts him on a collision course with Tom that will change everyone's lives forever.
Red and the Task Force place Dembe undercover to infiltrate an international human smuggling organization, but when communication is lost, they must intervene. Meanwhile, Tom's investigation into the suitcase lands him in grave danger.
While Cooper enlists Red on a case of personal importance, Ressler leads the Task Force on a mission to stop the resurgence of once-dormant murder-for-hire ring. Determined to find answers, Tom disregards a warning to halt his investigation into the suitcase.
When Red provides exclusive intel on an international terrorist, it puts Liz and the Task Force on a collision course with a rival unit from the CIA. Meanwhile, Red and Hawkins lay the groundwork for their new business venture; and Tom goes undercover in search of information.
The Task Force hunts for an elusive criminal who will stop at nothing to destroy some of the world's most precious treasures. Meanwhile, a surprise encounter leads a cash-strapped Red toward a new business opportunity.
While the Task Force investigates a series of suspicious police shootings, Agent Ressler is distracted by increasing external pressures. With his back up against the wall, Red drafts Tom in executing an elaborate plan to help re-establish his criminal reputation.
Liz and the Task Force join Red in pursuit of a billionaire who moonlights as a high end art thief. Meanwhile, Dembe chases a lead and Tom seeks outside help in identifying the remains in the suitcase.
In the Season 5 premiere, Red—whose criminal empire is in ruins—enlists Liz in an unlikely plan to simultaneously earn cash and deliver a new Blacklister to the Task Force. As Liz faces the new reality of working alongside her father, Ressler finds himself in a precarious position and Tom weighs his options.