Two nerdy physicists share an apartment and an unlikely friendship with their beautiful neighbour with whom one of them is infatuated. Like the universe after the big bang, the show's popularity expanded, thanks to breakout star Jim Parsons, along with the chemistry among the friends and the developing romance between Leonard and Penny. The addition of Melissa Rauch and Mayim Bialik in later seasons also enhanced the stories and relationships of the leads.
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Charlie Harper's Malibu lifestyle is interrupted when his brother and nephew stay with him. Briskly written and performed, the sitcom had fun spoofing Charlie Sheen's bad-boy reputation (which ultimately led to his exit from the series) and Jon Cryer's nervous energy.
An offbeat comedy drama series, which gained a loyal cult following and enthusiastic press during its five-season run, Northern Exposure concerned Dr. Joel Fleishman (Rob Morrow), a recent medical school graduate who attended Columbia University on a scholarship that stipulated that after graduation, he had to spend four years working as a general practitioner in the small town of Cicely, AK, where he is to be paid the princely sum of 465 dollars a month. As Fleishman bides his time in Cicely, he gets to know many of the local residents, including Maurice Minnifield (Barry Corbin), a multi-millionaire former astronaut who is the city's largest property owner; Maggie O'Connell (Janine Turner), a bush pilot (and the town's mayor) who has an on-again, off-again romance with Fleishman; Chris Stevens (John Corbett), the philosophical DJ at the local radio station; Holling Vincoeur (John Cullum), the owner of a local watering hole who has married Shelly Marie (Cynthia Geary), a young woman who was once in love with Maurice; Ed Chigliak (Darren E. Burrows), a genius-IQ teenager who wants to become a filmmaker; and Marilyn Whirlwind (Elaine Miles), a soft-spoken Native American who serves as Fleishman's receptionist.