In the Season 7 opener, Castiel assumes his new role as God and warns Sam and Dean to not interfere with him. Meanwhile, Dean tries to persuade Death to stop Castiel; and Sam struggles with the broken wall in his head.
Sam experiences hallucinations caused by the broken wall in his head. Meanwhile, Castiel struggles with his newfound power; and Bobby worries about Dean as he tries to fight Castiel and take care of Sam.
Sam and Dean are cloned by two Leviathans who go on a killing spree as the two brothers, which lands the real Sam and Dean on the FBI's most wanted list. Meanwhile, Bobby tries to find a way to kill the Leviathans.
A Winchester wedding is planned. Meanwhile, Sam gets involved in a confrontation with someone from his past, and Dean reluctantly teams up with another hunter when he finds himself in a situation that he cannot explain.
Sam and Dean hunt a mysterious creature that is attacking people in a New Jersey state park. Local townsfolk believe the creature is the legendary Jersey Devil. While in town, Dean discovers that a restaurant's special sandwich is making people crazy.
A demon that once murdered women in a small town resurfaces and embarks on another killing spree. Sam and Dean visit a man once possessed by the demon to see if he can remember any of the demonic beast's plans.
Sam and Dean investigate after a ballerina dances herself to death, and their probe reveals that the ballet slippers the victim wore are cursed. When Dean accidentally touches them, the curse takes hold of him.
Sam and Dean must locate three key items to defeat Dick Roman and the Leviathans, and Castiel aids them in their request. Meanwhile, Bobby attempts a new ghost trick that turns out to be extremely dangerous.