Abby must face the future and all its unknowns, after her daughter headed off to college and Barbara moving to New York; Phoebe frets that her newfound romance with Tess will be over before it starts; Delia must decide how to handle her unexpected pregnancy; Jo must decide between Frumpkis and Albert; all the girlfriends gather to celebrate Lilly's graduation; and a surprising coda answers many questions.
Abby is forced to play full-time stepmom now that Colette has relocated to Sacramento. Delia tells the girlfriends that the IVF worked and that she's pregnant - but Phoebe pieces together that the baby must be Tony's. Jo playacts through a weekend getaway with Albert but finally confesses that she kissed Frumpkis. Phoebe takes a chance on Tess. Abby must face the truth about her relationship with Mike, and she makes a harrowing decision.
Abby and Colette, Mike's ex-wife, clash over boundaries. Jo and Frumpkis deal with a family emergency that leaves Albert feeling challenged. After Delia receives some discouraging news from her fertility doctor, she throws caution to the wind and gets more involved with Tony. Phoebe finds herself unexpectedly drawn to an enigmatic new acquaintance.
Phoebe dips a toe back into the online dating pool only to find it's freezing cold; Abby is determined to blend the Brady and McCarthy families seamlessly, but Mike's new travel schedule causes some growing pains; Barbara confronts her ex-husband and her sister during a school function; and Delia moves forward with in vitro fertilization.
Abby and Jake fall into old confrontational patterns when Jake objects to Mike moving in with Abby. Albert plans a semi-surprise birthday party for Jo, which is disrupted by a visit from Jo's former mother-in-law, Meryl Frumpkis. Phoebe finally introduces Tony to her friends. Delia makes a potentially life-changing decision.
At a red-carpet event, Abby and the girlfriends flash back to their struggles and victories over the past six months. Abby makes an impetuous offer to Mike. Barbara lets her guard down around her ex-husband Leon. Delia gets some disappointing news—and then a surprising offer. Phoebe weighs the pros and cons of letting her brother Tony back into her life.