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Johnny heads up a team of huskies in one of the most difficult races in the world: a grueling 500-mile race through the mountains of Wyoming. Bozo is a Labernois a new cross-breed between a Lab and a Bouvier Bernois. His owner Chantal Jutras is in a wheelchair due to a muscular disease. Flip-Flop is a four-year-old mutt who gets suited up to brave the cold British seas with his owner David Samuel.
Yukon is an American-Canadian white shepherd who works in the Alps to rescue skiers and snowboarders caught in avalanches. Biggles and company follow their noses in a popular new kind of hunt through the English countryside. A German shepherd called Kodak trains to make the daring leap across a chasm in the Wisconsin Dells where dogs have been entertaining tourists for generations.
At the local hospital, Kiyoshi gentle presence calms and distracts troubled patients and their families. At the nearby elementary school, Kiyoshi listens to kids who have problems reading. Brix, a German shepherd, works with his handler Gordon Nash to fight crime in a tourist spot. Ellie, a Cavalier King Charles Spaniel, wins hearts when she adopts a family of orphaned rabbits.
Marty is the star of The Madcap Mutts, a dazzling troop made up of dogs rescued from shelters. Tasha is a shepherd mix who works with 17-year-old Stephanie, pulling her wheelchair and helping her with everyday tasks. An Akita with a history of biting, Nana has to learn obedience and agility -and do it fast, if she wants to stay with her family in Tokyo.