Forensic anthropologist Temperance "Bones" Brennan and her team work with the FBI to solve murders by identifying victims from their remains in a procedural series inspired by real-life forensic anthropologist and novelist Kathy Reichs.
The eighth season begins three months after Brennan went on the run from the FBI, but the Jeffersonian team is doing everything it can to prove that she was framed for murder by diabolical genius Christopher Pelant, and their case gets a boost from an anonymous tip that leads to the discovery of a high-school guidance counselor's remains.
The Jeffersonian team's investigation of the murder of a polarizing divorce lawyer takes a strange turn when they learn that important evidence has been hidden by the man's widow and assistant. Meanwhile, Brennan tries to get back into a normal routine, but her three-month separation from Booth is making it difficult.
An investigation of human remains found in the aftermath of an explosion in a hotel garage hits a snag when the team learn their assumptions about a man's fate are incorrect. Meanwhile, Sweets gets a temporary partner at the FBI when Booth has to work on the department's budget, which could lead to a promotion.
The team's investigation of the death of an animal-expo worker leads them into the shady market for illegal animal trading. Meanwhile, Brennan considers her political aspirations; and Sweets and Daisy confront a change in their relationship.
Brennan's new fascination with basketball and legendary coach Phil Jackson's thoughts on teamwork prompts her to gather five of her best "squinterns" to analyze remains that have never been identified. In the process, they try to identify a man who died in the 9/11 attacks and determine whether he was a perpetrator or a victim.
A street artist who is plastering his work on a billboard falls into his glue—and onto a corpse—so the team try to get him unstuck from the remains as they also work to identify the body. Meanwhile, Booth takes a stab at stand-up comedy at a club's open-mike night to look for suspects; and Angela finds herself attracted to the street artist.
Hodgins fears that Christopher Pelant is back for revenge after he and Angela are drugged, and a corpse is found in their bed canopy while flower petals are spread around their son's crib. In the ensuing investigation, the team discover the body belongs to a Special Forces agent linked to a soldier-for-hire organization, but Hodgins and Angela ignore Booth's request to let the FBI handle the case and start a probe of their own.
Daisy's first case since breaking up with Sweets is a doozy: the remains of two bodies, one a female cancer patient, the other her life coach, found at the same burial site. Meanwhile, Brennan and Booth discuss their preferences for funeral arrangements after they die.
Angela goes undercover on the roller-derby circuit after a skater's dismembered body is discovered. Meanwhile, Cam wonders if Booth is having an affair when she sees him having lunch with an unknown woman.
Brennan is shot while working late at the lab, but her condition is further complicated by logic-defying visions of her deceased mother. Meanwhile, the team's investigation of the incident reveals that the perpetrator may be linked to the Jeffersonian.
The remains of a 15-year-old boy are the subject of an investigation that begins to paint an unflattering portrait of the teen, who is initially remembered as being smart though socially awkward, but is ultimately linked to illegal behavior and allegations of rape. Meanwhile, Finn wonders if he should tell Cam that her daughter is in town for the weekend.
New intern Oliver Wells unnerves Brennan with his unusual observations and impressive logic, which make her consider scientific theories she would have previously ruled out. Meanwhile, Booth balks at Brennan's embrace of time travel as a possible explanation during a murder investigation.
The remains of an immigrant from Sierra Leone are discovered in a barrel at a disposal facility for hazardous waste. Meanwhile, Cam and Arastoo try to keep their relationship under wraps; and Brennan and Booth discuss their vacation plans.
An investigation of the death of a U.S. marine reveals the deceased's obsession with the apocalypse and a link to a group of doomsday preppers. Meanwhile, Sweets finds an apartment he loves, but Brennan and Booth doubt that he'll move out of their house.
An undercover police officer who was investigating ATM robberies is murdered and found with a bag of diamonds inside his mutilated body. Meanwhile, Brennan's stiff personality is no asset when she's the subject of a documentary commissioned to raise money for the Jeffersonian.
The murder of a TV producer is investigated. Meanwhile, Brennan is shocked by Christine's behavior when she's accused of biting a classmate; and Hodgins turns the lab into a test kitchen in an effort to duplicate intern Finn's hot sauce.
The death of a journalist at a biohazard facility sparks fear of a viral outbreak, but the search for the cure intensifies when Jeffersonian intern Arastoo Vaziri is infected with the same mutated virus that killed the reporter.
The Season 8 finale features more treachery from Christopher Pelant, who may have something to do with a series of murders that are linked to FBI agents close to Booth, which could mean he is the evil genius' next target.