Amanda teams up again with Tia of Pit Bulls and Parolees to help Aiden, a Great Dane mix with a brain issue. Then, she meets Chickpea, a French bulldog with a medical condition that quickly turns into a life or death situation.
Felines take over when Amanda helps an energetic kitten facing euthanasia after breaking his leg for a second time, along with a tiny kitten born with malformed front legs. Also, a 3-legged Husky-Rottweiler pup needs a forever home.
Amanda and her kids travel to Hawaii, where they meet dogs perfect for Panda Paws: a deaf mother-daughter Catahoula duo; Loco Moco, a puppy who may be blind; and Super Scootie, a senior in need of a home after years of neglect.
The rescue receives two new residents, including Professor Clovis, a miniature schnauzer with a suspected liver shunt who needs a complicated and costly surgery and Hamburglar, a blind puppy who Amanda prepares for his new forever family.