Patrick Dempsey and Ellen Pompeo by Bob D'Amico/ABC Patrick Dempsey and Ellen Pompeo by Bob D'Amico/ABC

As part of TV Guide's coverage of the new season of television, we'd like your answers to this second batch of "Returning Favorites" questions. Simply click on each, and then vote!

Should Mer and Der get married this season on Grey's Anatomy?

Who do you think got blown up in the SUV on Criminal Minds?

Can House and Wilson's friendship be saved?

Who do you think shot Horatio on CSI: Miami?

Who do you think are the real soulmates on How I Met Your Mother?

MORE POLLS: Click here for questions about Lost, CSI, Desperate Housewives, The Game and ER.