Oprah Winfrey is about to breathe new life into ailing cable channel Oxygen. The talk queen — who owns 25 percent of the network — will star in a prime-time companion to her daily syndicated chatfest. Oprah After the Show will tape immediately following her talk show and air weeknights on Oxygen at 7:30 pm/ET beginning Sept. 16. "We're going to kick off our shoes, take questions from the audience and see where the conversation takes us," Winfrey said. As part of the deal, Oxygen agreed to give up any rights to air reruns of The Oprah Winfrey Show — a deal it secured when Winfrey signed on as an investor.