Actress Isabel Sanford — aka Louise "Weezie" Jefferson from The Jeffersons — has died at 86. On July 4, she was hospitalized at L.A.'s Cedars-Sinai Medical Center, where she passed away on Friday with her daughter at her side. Sanford's health reportedly had been in decline since undergoing surgery on a neck artery last year. Back in 1981, Sanford was the first African-American woman to receive an Emmy for Best Actress in a Comedy Series. Most recently, the beloved TV personality did The Simpsons, as well as popular ad campaigns for Old Navy and Denny's restaurants.