April (Sarah Drew), Grey's Anatomy
Shonda Rhimes missed a big opportunity when she chose to kill off newbie Reed instead of April, much to everyone's chagrin, in the Season 6 finale. Whiny, clueless, nauseatingly cutesy and naive, and pretty much useless as a doctor and chief resident, April sucks the life out of most scenes despite the show's best attempts to make her likable (see: hooking up with Jackson). How April got two guys to fall for her, we'll never know. C'mon, Shonda, there has to be another natural disaster in the forecast.