1 of 10 Virginia Sherwood/NBC
Brooke Shields returns to the small screen in NBC's Lipstick Jungle.
2 of 10 Fred Norris/The WB
Chad Michael Murray's all grown up on One Tree Hill's all-new season.
3 of 10 Richard Cartwright/ABC
Is Eli Stone's Jonny Lee Miller ABC's new prophet
4 of 10 Adam Taylor/CBS
Julia Louis-Dreyfus returns for more New Adventures of Old Christine.
5 of 10 Isabella Vosminkova/FOX
Lena Headey is TV's new powergal in Terminator: The Sarah Connor Chronicles.
6 of 10
Cashmere Mafia's Lucy Liu is one sexy, power-driven woman!
7 of 10 Mario Perez/ABC
Can Lost's Matthew Fox lead his fellow islanders to safety this season
8 of 10 Jeff Neira/FOX
Nikolaj Coster Waldau seeks true love to lift his curse on Fox's New Amsterdam.
9 of 10 Richard Foreman/FOX
Parker Posey stars in the anticipated Return of Jezebel James.
10 of 10 Cliff Lipson/CBS
Thanks to the fans, Jericho's back, but can Skeet Ulrich save the town