The weird yet relatable voices of a generation, Jacobson and Glazer have graced the world with their phenomenal and wickedly hilarious series Broad City, which just so happens to be produced by Amy Poehler. Broad City fans should also check out the web series that inspired the Comedy Central show.
The stand-up regular made such a splash with her Weekend Update appearances on Saturday Night Live that she joined SNL soon after as a full cast member. Now she's slated to appear in a handful of comedy films including the Ghostbusters reboot.
Voice of Bob's Burgers' Louise, wife to The Last Man on Earth, and sometime Daily Show contributor, Schaal is always on point with her sharp perspective and singular voice.
Actress/comedian Williams balances her time dishing out truths as a The Daily Show with Jon Stewart correspondent with popping up in NYC comedy venues and on comedy series like HBO's Girls.
Saturday Night Live. Parks and Rec. The Golden Globes. The World! Poehler is a bonafide star taking over film and TV, but she's also co-founder of the Smart Girls at the Party online community and producer of Broad City and Welcome to Sweden.
Not to be outdone by "sister" Poehler (they're to play sisters in the summer comedy aptly named Sisters), Fey is a multi-hyphenate comedy juggernaut, creator of the critically acclaimed 30 Rock and Netflix comedy, Unbreakable Kimmy Schmidt. Can anyone stop the powerhouse that is Fey-Poehler? The answer, of course, is no. But a better question would be: why would anyone ever want to?
We still can't get enough of beloved SNL vet Rudolph's impersonations including everyone from Beyoncé to Nuni. Also known for her indie film work and her star-tastic variety show pilot, she's set to appear in the IFC miniseries The Spoils Before Dying with Bridesmaids co-star Kristen Wiig.
This Canadian-born comedienne and author holds the title of longest-serving The Daily Show correspondent of all time. Recently announcing her departure from the political satire series, she'll star in her own politically bent comedy show on TBS.
Everyone does want to hang out with Mindy as she's the star of her own show, The Mindy Project, and a The Office alum. Her next project, Why Not Me?, will be a followup to her 2011 memoir Is Everyone Hanging Out Without Me? (And Other Concerns).
Outspoken comic known for her New York Times best sellers, including Uganda Be Kidding Me, and scathing celebrity commentary, Handler rocks at stand up, hosting, writing and more. She makes a smooth transition from Chelsea Lately, which ended in 2014, to a new talk show to debut on Netflix in 2016.
The longtime stand-up comedienne made a splash creating and starring in her eponymous ABC sitcom, proving that sitcom is anything but just a white man's game.
The former Riot Grrrl, writer, musician (Sleater-Kinney) and actress is probably best known for co-creating and performing in the sketch series, Portlandia with Fred Armisen. She's still performing onstage, however, as a member of the all-female supergroup Wild Flag.
Everything's coming up Amy Schumer. Just as the third season of her Comedy Central series is scheduled to premiere, she's set to host the 2015 MTV Movie Awards and star in the Judd Apatow-directed Trainwreck, which she also wrote.
At 93, White has had a long, successful career in comedy and holds the Guinness World Record for longest TV career for a female performer. She's anything but down and out, as she's set to receive the Lifetime Achievement Award at the 42nd Annual Daytime Emmys.
Another new addition to Saturday Night Live, Zamata first gained a following thanks to her web appearances including sketches from her YouTube channel and the webseries Pursuit of Sexiness.
Their real names, by the way, are Kate Micucci and Riki Lindhome, but the most important thing to know is that they're hilarious. Folky, comedic songs have never sounded as good as in their YouTube music videos and gone-too-soon IFC series.
Silverman has had a long, varied career--including SNL appearances, The Sarah Silverman Program, and stand-up specials--which shows no signs of stopping. Silverman recently has been breaking into more dramatic roles such as on Showtime's Masters of Sex and indie movies like I Smile Back with Josh Charles.
A regular at Upright Citizens Brigade Theatre, Byer received national attention for her GIF-able commentary and reactions on MTV's Girl Code. Along with Zamata and Keisha Zollar, she was part of the Doppelganger comedy troupe, but currently, she can be found in various MTV promotions and TV spots.
The voice and co-creator of Marcel the Shell with Shoes On has so far enjoyed a career that has moved at anything but a snail's pace. From memorable spots on Parks and Recreation and Kroll Show to her critically acclaimed performance in Obvious Child, Slate is (obviously) slated for more good things to come.
From lovable chef Sookie on Gilmore Girls to international superstar, McCarthy is the current queen of comedy movies, skyrocketing to success after her memorable role in Bridesmaids. She's set to star in the summer action comedy Spy as well as the all-female Ghostbusters sequel, featuring a couple (read: a bunch) of the women in this gallery.
Breaking barriers and boundaries is all in a day's work for this comic/writer/actor/singer. Noted for her activist campaigns, she's working on a documentary centered around San Francisco homelessness. Elsewhere, she co-hosts TLC's late night talk show All About Sex and tours the country doing stand-up.
With a Netflix special, recurring appearances on Kroll Show and a regular role on Fox's Brooklyn Nine-Nine, Peretti has established herself as a fixture of TV comedy. Along with acting and stand-up, she's also a TV writer, credited for six episodes of Parks and Recreation.
Two words: crushed it. While Super Fun Night didn't make much of an impact, Wilson still rules the stand-up stage and steals movie scenes as the breakout star of Pitch Perfect and the upcoming Pitch Perfect 2.
The Queen of Daytime Talk Shows, Degeneres first gained national acclaim for her stand-up performances and ABC sitcom, Ellen. Now she can be expected to dance up a storm, prank celebrities and surprise deserving individuals with prizes and more on The Ellen Degeneres Show.
Hot off her Emmy award win for Veep, Louis-Dreyfus is in yet another of several sizzling streaks in her career which spans her lauded role as Elaine on Seinfeld, starring in The New Adventures of the Old Christine and her early years on Saturday Night Live.
With her stand-up career still going strong, the comic and actress also helps other comics get their big break, acting as executive producer of Last Comic Standing. While she first worked for the NSA before getting into comedy, Sykes returned to DC (in a way) by playing a Democratic senator in Amazon's Alpha House.
Not quite a household name just yet, she'll get there soon enough thanks to her great and bizarre brand of comedy. An actress, writer and comic, she wrote and regularly appeared on Totally Biased with W. Kamau Bell, performs stand-up, serves as contributing editor to The Offing online magazine and appears in the web series Your Main Thing.
A noted SNL alum, Wiig proved she can rock at more than just sketch comedy with smash hit Bridesmaids. Branching out from her comedy roots, the writer-actress has a mix of comedic and dramatic upcoming roles in movies such as The Martian, The Diary of a Teenage Girl and Ghostbusters.
Known for her riotously funny deadpan comedy, Notaro is a big name in the stand-up comedy tour world. The Grammy-nominated comic has documented her latest tour for fans across the country in the upcoming Showtime special, Knock, Knock It's Tig Notaro.
Creator and star of YouTube sensation The Misadventures of Awkward Black Girl, Rae has recently released a book of essays of the same name. Soon she could be bringing her signature awkward-cool to HBO as her comedy Insecure has been given a pilot order.
McKinnon uses her knack for accents to make big and bold impressions on Saturday Night Live. Who else can channel both Justin Bieber and Ruth Bader Ginsburg? Alongside SNL alums Fey and Poehler, she'll appear in the comedy Sisters. Plus, she'll round out an all-female, all-funny cast of the Ghostbusters reboot.
If you haven't done so already, "treat yo self" to the comedic stylings of Retta, known for her portrayal of Parks and Recreation's Mercedes-driving, man-eating Donna Meagle. If you're not following Retta on Twitter, where she live tweets her favorite shows better than the rest of us, then you're doing Twitter wrong.
Before she starred in Unbreakable Kimmy Schmidt, Kemper made steady, memorable appearances in Bridesmaids, 21 Jump Street and The Mindy Project. For The Office fanatics, however, she's still best known as the wacky receptionist with a heart of gold, Erin.