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Oh hey, Ryan Reynolds!

Julia Lechner
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During its nine seasons, Scrubs was filled with A-list guest stars, from Ryan Reynolds to Elizabeth Banks. These are the major celeb appearances you may have forgotten about...

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Heather Locklear

The Melrose Place alum appeared as pharmaceutical rep Julie Keaton. She was known for flirting with everyone in the hospital and for briefly dating Dr. Cox.

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Scott Foley

The Scandal star appeared numerous times on the show as Elliot Reid's Sea World dolphin trainer boyfriend Sean Kelly. He ultimately coupled up with J.D.'s ex and baby mama Kim Briggs (played by Elizabeth Banks).

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Elizabeth Banks

Speaking of Banks, the Hunger Games star had a run on Scrubs as a urologist who ended up co-parenting her baby with J.D.

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Julianna Margulies

The Good Wife's Margulies guest-starred in a two-episode arc on the series as attorney Neena Broderick. She had a brief sexual relationship with J.D. while suing his best friend Turk for malpractice.

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Heather Graham

The Hangover star played a psychiatrist and Elliot's BFF, Dr. Molly Clock, on several episodes of Scrubs. She was sweet and spacey and had a bad habit of being attracted to dysfunctional people.

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Michael J. Fox

The TV veteran and Back to the Future star appeared on two episodes as Dr. Kevin Casey, a medical professional dealing with OCD. He also had an issue with using rooftop "epiphany" toilets.

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Matthew Perry

The Friends alum guest-starred on one episode as a man who has to be convinced to donate a kidney to his estranged dad ... who was played by his real-life father, John Bennett Perry.

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Mandy Moore

This Is Us star Mandy Moore appeared opposite her once real-life boyfriend Zach Braff (J.D.) to play his on-screen girlfriend Julie Quinn. She was known for being the klutzy goddaughter of Billy Dee Williams.

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Billy Dee Williams

The iconic actor made a cameo on the series, where he had to deal with Turk annoyingly calling him by his Star Wars character's name "Lando Calrissian."

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Aziz Ansari

Before Parks and Recreation, Ansari appeared on Scrubs as an intern, Dr. Ed Dhandapani. Dr. Cox fired him for being too lazy to study.

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Brendan Fraser

The Mummy alum guest-starred on more than one episode of the show as a photographer and Jordan's lovable brother, Ben Sullivan. His untimely death, from cancer, deeply affected Dr. Cox.

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Colin Farrell

Remember that time Farrell played Billy Callahan on one episode of the comedy series? His character was an Irish man who wanted to visit a patient he sent to the hospital in a bar fight.

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Courteney Cox

The Friends alum played the "soulless" Dr. Taylor Maddox, who took over as the hospital's Chief of Medicine after Dr. Kelso quit. After Kelso blackmailed the hospital board into letting her go, she was later replaced by Dr. Cox.

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Dick Van Dyke

The legendary actor made one guest-starring appearance as Dr. Doug Townshend, a likable older doctor who was a favorite at the hospital. He was pushed into early retirement by his friend and colleague, Dr. Kelso, for not keeping up with modern medical practices.

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Jason Bateman

The Arrested Development actor guest-starred on one episode of Scrubs as a garbage man named Mr. Sutton who owned a pet ostrich. For real.

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Ryan Reynolds

Before he was Deadpool, Reynolds made a one-episode appearance as J.D. and Turk's college buddy Spence. He was responsible for dropping the bombshell that Dr. Cox was the father of Jordan's baby.

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Tara Reid

Reid's Danni Sullivan was Jordan's sister on the show and also sister to the late Ben Sullivan (played by Brendan Fraser.) She dated J.D. and, like him, had a running inner monologue.

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John Ritter

As J.D. and Dan Dorian's father, Sam Dorian, the late actor starred as a traveling office supply salesman who was known for his generous spirit and his "pull my finger" jokes.

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Kareem Abdul-Jabbar

The basketball legend made a brief cameo on the show as himself, visiting a patient who was about to be discharged. J.D. also accused Abdul-Jabbar of being a psych ward patient named Mr. Rosenberg.

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Keri Russell

Russell guest-starred as Elliot Reid's wild sorority sister Melody O'Harra, who loved making out and partying.

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D.L. Hughley

The comedian played Turk's older brother, Kevin Turk, on the series. He helped his younger brother pay off his medical school tuition and loans.

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Maria Menounos

As Tamara on Scrubs, the TV personality dated J.D. only because she liked his hair. The ultimately broke up because he shaved his head.

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Tom Cavanagh

The Ed star made numerous Scrubs appearances as J.D.'s older brother, Dan Dorian. He wins J.D.'s approval by becoming a successful real estate agent after years of being an attic-dwelling part-time bartender.

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Clay Aiken

The American Idol runner-up guest-starred on one episode as cafeteria worker Kenny. He starred in J.D.'s "sitcom fantasy" and sang in a hospital talent show. Unfortunately, in the real timeline of the show, he was fired due to budget cuts.