- Spent part of his childhood in a Ghana fishing village, where his parents helped build an education system.
- Earned three degrees, in English, biology and education, from Queens University; worked as a teacher before his acting career took off.
- Won a 2001 TV GUIDE Award for Actor of the Year in a New Series for Ed.
- Bearing a striking resemblance to actor Zach Braff, he played his older brother in a recurring role on Scrubs.
- In 2008, played a professor in an off-Broadway production of the play Some Americans Abroad.
- Starred as a detective in The Capture of the Green River Killer (2008), Lifetime's first original miniseries.
- In 2009, paired with Eric McCormack to headline TNT's short-lived drama series Trust Me.
- 2002, Golden Globe — Best Performance by an Actor in a Television Series - Musical or Comedy: Nominee
- James Joseph Cavanagh — Son
- Thomas Cavanagh Sr. — Father
- Alice Ann Cavanagh — Daughter
- Rosemary Cavanagh — Mother
- Maureen Grise — Wife
- Thomas Patrick Cavanagh — Son
- Queens University, Kingston, Ontario, Canada
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