- Both parents are native South Africans who immigrated to the United States in the 1990s.
- Mother was a cast member on the sports entertainment TV show UK Gladiators in the mid-1990s, performing under the name Laser.
- Trains primarily at a two-lane swimming facility in the backyard of the family home, where his father, a former diver in the South African Navy, serves as his coach.
- Utilizes a controversial training method called ultra-short, race-pace training, or USRPT, which calls for a swimmer to practice at optimal speed and puts less emphasis on distance training.
- Signed his first endorsement deal in 2013 at the age of 14, making him the youngest professional swimmer in United States history.
- Has broken over 70 National Age Group records during a prodigious youth swimming career.
- Won five medals at the 2015 World Junior Championships, including gold in the 50m backstroke.
- Signed a multi-year partnership with Adidas in 2015.
- Michaela Andrew — Sister
- Peter Andrew — Father
- Tina Andrew — Mother